Description

Methyl 5-Bromo-7H-Pyrrolo[2,3-D]Pyrimidine-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the pyrrolopyrimidine class of heterocyclic compounds. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of targeted therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Used in the synthesis of probes for studying enzyme function and cellular signaling pathways in academic and industrial R&D.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the multi-step synthesis of complex active molecules during process development and scale-up.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials and commercial APIs.

Basic Information

Product Name	Methyl 5-Bromo-7H-Pyrrolo[2,3-D]Pyrimidine-4-Carboxylate
CAS No.	1638767-47-1
Molecular Formula	C8H6BrN3O2
Molecular Weight	256.06 g/mol
Synonyms	5-Bromo-7H-pyrrolo[2,3-d]pyrimidine-4-carboxylic acid methyl ester; Methyl 5-bromo-7H-pyrrolo[2,3-d]pyrimidine-4-carboxylate; 5-Bromo-4-(methoxycarbonyl)-7H-pyrrolo[2,3-d]pyrimidine; 4-Carbomethoxy-5-bromo-7H-pyrrolo[2,3-d]pyrimidine; 5-Bromo-7H-pyrrolo[2,3-d]pyrimidine-4-carboxylate methyl ester; 1638767-47-1; 5-Bromo-7H-pyrrolo[2,3-d]pyrimidine-4-carboxylic acid, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-Bromo-7H-Pyrrolo[2,3-D]Pyrimidine-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP manufacturing. Certificates of Analysis (COA) with detailed specifications are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.