Description

2-Chloro-5-Methyl-5H,6H,7H-Pyrrolo[2,3-D]Pyrimidin-6-One is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrrolopyrimidine class of heterocyclic compounds. This compound is of significant value for its role as a critical building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, including kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries in drug discovery programs targeting various diseases.
• Kinase Inhibitor Synthesis: A crucial building block for the development of potent and selective kinase inhibitors, a major class of oncology and anti-inflammatory drugs.
• Agrochemical Research: Potential intermediate in the synthesis of novel herbicides or fungicides, leveraging its heterocyclic structure.
• Biochemical Tool Compound: Can be utilized in biochemical assays to study enzyme mechanisms or as a reference standard.
• Custom Synthesis & Contract Manufacturing: Supplied for custom chemical synthesis and scale-up processes under cGMP or research-grade conditions.

Basic Information

Product Name	2-Chloro-5-Methyl-5H,6H,7H-Pyrrolo[2,3-D]Pyrimidin-6-One
CAS No.	1638767-37-9
Molecular Formula	C7H6ClN3O
Molecular Weight	183.59 g/mol
Synonyms	2-Chloro-5-methyl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-6-one; 6H-Pyrrolo[2,3-d]pyrimidin-6-one, 2-chloro-5,7-dihydro-5-methyl-; 2-Chloro-5-methyl-5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one; 2-Chloro-5-methyl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-6-one; CAS 1638767-37-9
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Methyl-5H,6H,7H-Pyrrolo[2,3-D]Pyrimidin-6-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay purity and impurity profiles. Our quality systems are designed to support both non-GMP and cGMP supply chains, depending on customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.