Description

2-Amino-6-Bromo-8-Cyclopentyl-5-Methylpyrido[2,3-D]Pyrimidin-7(8H)-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly for its role as a key building block in the synthesis of targeted kinase inhibitors. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel therapeutic agents for oncology and other disease areas.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of novel drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new therapeutic molecules.
• Biochemical Tool Compound: Acts as a reference standard or a starting material for creating specialized probes in biochemical and pharmacological assays.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	2-Amino-6-Bromo-8-Cyclopentyl-5-Methylpyrido[2,3-D]Pyrimidin-7(8H)-One
CAS No.	1637781-10-2
Molecular Formula	C₁₇H₁₉BrN₄O
Molecular Weight	375.26 g/mol
Synonyms	2-Amino-6-bromo-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7-one; 2-Amino-6-bromo-8-cyclopentyl-5-methyl-7,8-dihydropyrido[2,3-d]pyrimidin-7-one; 1637781-10-2; 8-Cyclopentyl-2-amino-6-bromo-5-methyl-7,8-dihydropyrido[2,3-d]pyrimidin-7-one; 6-Bromo-8-cyclopentyl-2-amino-5-methyl-7,8-dihydropyrido[2,3-d]pyrimidin-7-one; Br-CPPMPO; Kinase Inhibitor Intermediate CPPO-2A6B
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-6-Bromo-8-Cyclopentyl-5-Methylpyrido[2,3-D]Pyrimidin-7(8H)-One is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the stringent requirements of pharmaceutical development. A detailed Certificate of Analysis (COA) with batch-specific results from HPLC, NMR, and MS is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.