Description

(5-Bromopyrimidin-2-Yl)Methanamine Hydrobromide is a high-purity, functionalized pyrimidine building block essential for advanced organic synthesis. This compound is critical for medicinal chemistry research and development, serving as a versatile intermediate for constructing complex molecular architectures. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers in the production of active pharmaceutical ingredients (APIs) and novel therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule drug candidates.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns for structure-activity relationship (SAR) studies.
• Agrochemical Development: Serves as a building block for creating novel pesticides and herbicides with specific biological activity.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and material science applications.
• Chemical Biology Probes: Used to develop molecular probes for studying biological pathways and target engagement.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	(5-Bromopyrimidin-2-Yl)Methanamine Hydrobromide
CAS No.	1632285-95-0
Molecular Formula	C5H7Br2N3
Molecular Weight	268.94 g/mol
Synonyms	2-(Aminomethyl)-5-bromopyrimidine hydrobromide; 1-(5-Bromopyrimidin-2-yl)methanamine hydrobromide; (5-Bromo-2-pyrimidinyl)methanamine hydrobromide; 5-Bromo-2-pyrimidinemethanamine hydrobromide; 5-Bromopyrimidine-2-methanamine HBr
EINECS	Contact for details

Quality Control

Our (5-Bromopyrimidin-2-Yl)Methanamine Hydrobromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.