Description

n-(Piperidin-4-Yl)-6-(2,2,2-Trifluoroethyl)Thieno[2,3-D]Pyrimidin-4-Amine is a high-purity, advanced pharmaceutical intermediate featuring a unique thienopyrimidine core. This compound matters for its critical role as a building block in the synthesis of targeted small-molecule therapeutics, particularly kinase inhibitors. Pharmaceutical R&D and process chemistry teams need this material for developing novel drug candidates in oncology and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel kinase inhibitors and other targeted small-molecule drugs.
• Oncology Research: Used in the discovery and development of anti-cancer agents targeting specific enzymatic pathways.
• Chemical Biology: Serves as a core scaffold for creating chemical probes to study protein function and cellular signaling.
• Process Development: Employed in route scouting, optimization, and scale-up activities for Active Pharmaceutical Ingredient (API) manufacturing.
• Custom Synthesis: A starting point for the preparation of specialized analogs and derivatives for structure-activity relationship (SAR) studies.

Basic Information

Product Name	n-(Piperidin-4-Yl)-6-(2,2,2-Trifluoroethyl)Thieno[2,3-D]Pyrimidin-4-Amine
CAS No.	1628317-93-0
Molecular Formula	C13H15F3N4S
Molecular Weight	316.35 g/mol
Synonyms	6-(2,2,2-Trifluoroethyl)-N-(4-piperidinyl)thieno[2,3-d]pyrimidin-4-amine; 4-Amino-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidine N-piperidin-4-yl; Thieno[2,3-d]pyrimidin-4-amine, 6-(2,2,2-trifluoroethyl)-N-4-piperidinyl-; 1628317-93-0; 6-(Trifluoroethyl)thienopyrimidine piperidine amine; CAS 1628317-93-0
EINECS	Contact for details

Quality Control

Our n-(Piperidin-4-Yl)-6-(2,2,2-Trifluoroethyl)Thieno[2,3-D]Pyrimidin-4-Amine is manufactured under strict quality systems to ensure batch-to-batch consistency suitable for research and development. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.