Description

6-(2,2,2-Trifluoroethyl)Thieno[2,3-D]Pyrimidin-4(3H)-One is a high-value heterocyclic building block and pharmaceutical intermediate characterized by its fused thienopyrimidinone core and trifluoroethyl substituent. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel small molecule therapeutics targeting various disease pathways. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical innovators, and advanced material scientists seeking to incorporate its unique fluorine-containing scaffold into new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other enzyme-targeting molecules.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Employed in the research and synthesis of novel active ingredients for crop protection products.
• Chemical Biology Probe Synthesis: Utilized to create tool compounds for investigating biological pathways and target validation.
• Material Science Research: Acts as a building block for developing advanced organic electronic materials or specialty polymers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting outsourced R&D and scale-up activities for the life sciences industry.

Basic Information

Product Name	6-(2,2,2-Trifluoroethyl)Thieno[2,3-D]Pyrimidin-4(3H)-One
CAS No.	1628317-84-9
Molecular Formula	C8H5F3N2OS
Molecular Weight	234.20 g/mol
Synonyms	6-(2,2,2-Trifluoroethyl)-3H-thieno[2,3-d]pyrimidin-4-one; 6-(Trifluoroethyl)thieno[2,3-d]pyrimidin-4(3H)-one; Thieno[2,3-d]pyrimidin-4(3H)-one, 6-(2,2,2-trifluoroethyl)-; 1628317-84-9; 6-(2,2,2-Trifluoroethyl)thieno[2,3-d]pyrimidin-4-ol (tautomer); TFETP; CAS 1628317-84-9.
EINECS	Contact for details

Quality Control

Our 6-(2,2,2-Trifluoroethyl)Thieno[2,3-D]Pyrimidin-4(3H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is supplied with each batch to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.