Description

(1S, 3S)-N1-Methyl-N1-(7-Tosyl-7H-Pyrrolo-[2,3-D]Pyrimidin-4-Yl)Cyclobutane-1,3-Diamine Dihydro Bromide is a high-purity, advanced pharmaceutical intermediate with a defined stereochemistry. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of targeted kinase inhibitors. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel kinase inhibitors for oncology and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Preclinical Development: Serves as a critical starting material for producing active pharmaceutical ingredients (APIs) in small-scale GMP campaigns.
• Chemical Biology: Employed as a molecular probe to study specific biological pathways and enzyme functions.
• Process Chemistry: Used for route scouting and scale-up process development for new drug candidates.
• Reference Standard: High-purity material suitable for use as an analytical reference standard in quality control laboratories.

Basic Information

Product Name	(1S, 3S)-N1-Methyl-N1-(7-Tosyl-7H-Pyrrolo-[2,3-D]Pyrimidin-4-Yl)Cyclobutane-1,3-Diamine Dihydro Bromide
CAS No.	1622903-42-7
Molecular Formula	C19H25Br2N5O2S
Molecular Weight	547.31 g/mol
Synonyms	(1S,3S)-N1-Methyl-N1-(7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)cyclobutane-1,3-diamine hydrobromide (1:2); (1S,3S)-N-Methyl-N-(7-(4-methylphenyl)sulfonyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)cyclobutane-1,3-diamine dihydrobromide; UNII-3V8Q7J8F8H; 3V8Q7J8F8H; (1S,3S)-N1-Methyl-N1-(7-Tosyl-7H-Pyrrolo[2,3-d]Pyrimidin-4-yl)Cyclobutane-1,3-Diamine Dihydrobromide; (1S,3S)-N1-Methyl-N1-(7-(p-Tolylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)cyclobutane-1,3-diamine dihydrobromide
EINECS	Contact for details

Quality Control

Our (1S, 3S)-N1-Methyl-N1-(7-Tosyl-7H-Pyrrolo-[2,3-D]Pyrimidin-4-Yl)Cyclobutane-1,3-Diamine Dihydro Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and residual solvent analysis to ensure compliance with ICH Q3 guidelines. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.