Description

Carbamic Acid, n-[cis-3-[Methyl[7-[(4-Methylphenyl)Sulfonyl]-7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl]Amino]Cyclobutyl]-, Phenylmethyl Ester is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, particularly in the creation of targeted kinase inhibitors. It is primarily utilized by pharmaceutical manufacturers and advanced research institutions engaged in the development of novel therapeutics for oncology and other disease areas.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of novel kinase inhibitor drug candidates.
• Oncology Research: Used in the research and development of targeted cancer therapies, particularly those focused on specific protein kinases.
• Medicinal Chemistry: Serves as a crucial scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Employed in the scale-up and optimization of synthetic routes for potential API manufacturing.
• Biochemical Research: Used as a reference standard or tool compound in biochemical assays to study enzyme inhibition and cellular pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	Carbamic Acid, n-[cis-3-[Methyl[7-[(4-Methylphenyl)Sulfonyl]-7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl]Amino]Cyclobutyl]-, Phenylmethyl Ester
CAS No.	1622903-41-6
Molecular Formula	C26H27N5O4S
Molecular Weight	505.59 g/mol
Synonyms	Benzyl N-[(1s,3s)-3-[[7-[(4-methylphenyl)sulfonyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-methylamino]cyclobutyl]carbamate; (1s,3s)-3-[[7-[(4-Methylphenyl)sulfonyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-methylamino]cyclobutyl-carbamic acid benzyl ester; UNII-2V6F6V3Z0P; 2V6F6V3Z0P; Carbamic acid, N-[(1s,3s)-3-[[7-[(4-methylphenyl)sulfonyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]methylamino]cyclobutyl]-, phenylmethyl ester; Benzyl ((1s,3s)-3-((7-(p-tolylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)(methyl)amino)cyclobutyl)carbamate
EINECS	Contact for details

Quality Control

Our Carbamic Acid, n-[cis-3-[Methyl[7-[(4-Methylphenyl)Sulfonyl]-7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl]Amino]Cyclobutyl]-, Phenylmethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.