Description

Angiotensin(1-7) is a bioactive heptapeptide fragment of the renin-angiotensin system (RAS) with the CAS registry number 1620458-09-4. This compound is of significant interest for its counter-regulatory role to the classical ACE/Ang II/AT1R axis, offering potential therapeutic pathways. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life science sectors for cardiovascular, metabolic, and renal disease research, drug discovery, and diagnostic assay development.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating the Mas receptor pathway, vasodilation, anti-fibrotic effects, and anti-inflammatory responses.
• Pharmaceutical Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the preclinical development of novel therapeutics for hypertension, heart failure, and diabetes.
• Diagnostic Manufacturing: Employed in the production of immunoassay kits, ELISA tests, and other in-vitro diagnostic (IVD) reagents for quantifying RAS components.
• Cell Culture & Biochemistry: Applied in cell-based assays to study signal transduction mechanisms and as a tool compound to modulate cellular pathways in experimental models.

Basic Information

Product Name	Angiotensin(1-7)
CAS No.	1620458-09-4
Molecular Formula	C41H62N12O11
Molecular Weight	899.0 g/mol
Synonyms	Ang-(1-7); Asp-Arg-Val-Tyr-Ile-His-Pro; H-Asp-Arg-Val-Tyr-Ile-His-Pro-OH; Angiotensin I (1-7); Angiotensin 1-7; [Asp1, Arg2, Val3, Tyr4, Ile5, His6, Pro7]-Angiotensin I
EINECS	Contact for details

Quality Control

Our Angiotensin(1-7) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%
Bacterial Endotoxins	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.