Description

5-Hydroxypyrimidin-4(3H)-One Hydrochloride is a high-purity heterocyclic building block and pharmaceutical intermediate. This compound is critical for research and development in medicinal chemistry, particularly for the synthesis of novel drug candidates targeting various therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical companies, and fine chemical manufacturers engaged in advanced organic synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of nucleoside analogs, kinase inhibitors, and other active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies for drug discovery programs.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides, fungicides, and plant growth regulators.
• Biochemical Tool Compound: Utilized in biochemical assays to study enzyme mechanisms and metabolic pathways.
• Fine Chemical Production: Intermediate for the manufacture of specialty chemicals, dyes, and complex organic molecules.

Basic Information

Product Name	5-Hydroxypyrimidin-4(3H)-One Hydrochloride
CAS No.	1616526-82-9
Molecular Formula	C4H5N2O2•HCl
Molecular Weight	148.55 g/mol
Synonyms	4(3H)-Pyrimidinone, 5-hydroxy-, hydrochloride; 5-Hydroxy-4(3H)-pyrimidinone hydrochloride; 5-Hydroxypyrimidin-4-ol hydrochloride; 4-Hydroxy-5-hydroxypyrimidine hydrochloride; 5-Hydroxy-1H-pyrimidin-4-one hydrochloride; 5-Hydroxypyrimidin-4(1H)-one hydrochloride; 5-Hydroxy-4-pyrimidinol hydrochloride
EINECS	Contact for details

Quality Control

Our 5-Hydroxypyrimidin-4(3H)-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.