Description

5-Octyl-α-Ketoglutarate is a specialized alkyl ester derivative of α-ketoglutarate, a key intermediate in the Krebs cycle. This compound is valued for its enhanced lipophilicity and membrane permeability compared to its parent acid, making it a crucial building block in advanced biochemical and pharmaceutical research. It is primarily sought by R&D and production teams in the pharmaceutical, nutraceutical, and fine chemical synthesis industries for developing novel metabolic modulators and prodrugs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel prodrugs and active pharmaceutical ingredients (APIs) targeting metabolic pathways.
• Biochemical Research: Used as a cell-permeable substrate in studies of mitochondrial function, cellular energy metabolism, and the TCA cycle.
• Nutraceutical Development: Investigated for potential applications in dietary supplements aimed at supporting cellular energy production and metabolic health.
• Cosmetic Actives: Explored for use in advanced skincare formulations targeting cellular rejuvenation and anti-aging benefits.
• Organic Synthesis: Acts as a versatile building block for synthesizing more complex ester derivatives and specialty fine chemicals.

Basic Information

Product Name	5-Octyl-α-Ketoglutarate
CAS No.	1616344-00-3
Molecular Formula	C₁₃H₂₂O₅
Molecular Weight	258.31 g/mol
Synonyms	Octyl 2-Oxopentanedioate; Octyl α-Ketoglutarate; 2-Oxopentanedioic Acid Octyl Ester; α-Ketoglutaric Acid Octyl Ester; 5-Octyl 2-Oxoglutarate; AKG Octyl Ester; 2-Oxoglutaric Acid Octyl Ester
EINECS	Contact for details

Quality Control

Our 5-Octyl-α-Ketoglutarate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong alkalis and incompatible organic solvents. For long-term storage, consider inert gas purging to minimize oxidation risk.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.