Description

2,4-Dichloro-6-Fluorobenzyl Alcohol is a versatile halogenated benzyl alcohol derivative that serves as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in its unique substitution pattern, which provides a reactive benzylic alcohol site adjacent to a halogenated aromatic ring, enabling a wide range of chemical transformations. This compound is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical and agrochemical industries for constructing complex molecules, including active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development and production of advanced herbicides, fungicides, and insecticides, where the dichloro-fluoro substitution pattern contributes to biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic components used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Acts as a monomer or chain modifier in the production of specialty polymers, including high-performance resins and engineering plastics with enhanced properties.
• Cross-Coupling Reactions: The benzylic position and halogenated ring make it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create complex biaryl structures.
• Protecting Group Chemistry: The benzyl alcohol functionality can be used to introduce and later remove protecting groups in multi-step synthetic sequences.
• Chemical Research & Development: Employed in academic and industrial R&D settings for method development, library synthesis, and exploring new chemical spaces.

Basic Information

Item	Details
Product Name	2,4-Dichloro-6-Fluorobenzyl Alcohol
CAS No.	1615212-18-4
Molecular Formula	C7H5Cl2FO
Molecular Weight	195.02 g/mol
Synonyms	(2,4-Dichloro-6-fluorophenyl)methanol; 2,4-Dichloro-6-fluorobenzenemethanol; 6-Fluoro-2,4-dichlorobenzyl alcohol; α-Hydroxymethyl-2,4-dichloro-6-fluorobenzene; 1-(Hydroxymethyl)-2,4-dichloro-6-fluorobenzene; 2,4-Dichloro-6-fluoro-α-hydroxy toluene
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-6-Fluorobenzyl Alcohol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the stringent requirements for use in regulated synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.