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9-(3-Deoxy-3-Fluoro-β-D-Ribofuranosyl)-6-[6-(4-Methylpiperazinyl) Pyridin-3-Yl]Purine CAS NO 1612191-99-7
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CAS No.:1612191-99-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
9-(3-Deoxy-3-Fluoro-β-D-Ribofuranosyl)-6-[6-(4-Methylpiperazinyl) Pyridin-3-Yl]Purine is a high-purity nucleoside analog building block of significant interest in advanced pharmaceutical research and development. This compound matters as a key synthetic intermediate for the creation of novel antiviral and anticancer agents, leveraging its modified sugar and purine base structure. It is primarily needed by R&D laboratories, process development chemists, and manufacturers in the pharmaceutical and biotechnology sectors focused on nucleoside-based therapeutics.
Application
- Pharmaceutical Intermediate: Critical building block for the synthesis of novel nucleoside analog drugs targeting viral infections.
- Antiviral Drug Development: Used in research for potential therapeutics against a range of viruses, including hepatitis and herpesviruses.
- Oncology Research: Serves as a precursor in the development of purine-based anticancer compounds and targeted therapies.
- Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies to understand nucleoside metabolism and related pathways.
- Process Chemistry: Utilized in scale-up and optimization studies for the commercial manufacturing of active pharmaceutical ingredients (APIs).
- Medicinal Chemistry: A versatile scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
Basic Information
| Item | Details |
|---|---|
| Product Name | 9-(3-Deoxy-3-Fluoro-β-D-Ribofuranosyl)-6-[6-(4-Methylpiperazinyl) Pyridin-3-Yl]Purine |
| CAS No. | 1612191-99-7 |
| Molecular Formula | C20H25FN8O3 |
| Molecular Weight | 444.46 g/mol |
| Synonyms | 6-[6-(4-Methyl-1-piperazinyl)-3-pyridinyl]-9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)-9H-purine; 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[6-(4-methylpiperazin-1-yl)pyridin-3-yl]purine; Fluorinated nucleoside analog with methylpiperazinyl-pyridinylpurine; 1612191-99-7; 9H-Purine, 6-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]-9-(3-deoxy-3-fluoro-β-D-ribofuranosyl)- |
| EINECS | Contact for details |
Quality Control
Our 9-(3-Deoxy-3-Fluoro-β-D-Ribofuranosyl)-6-[6-(4-Methylpiperazinyl) Pyridin-3-Yl]Purine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with complete batch data are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (HPLC) | Conforms |
| Identification (NMR) | Conforms |
| Purity (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 1.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
| Heavy Metals | < 10 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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