Description

1-(4,6-Dichloro-5-Fluoropyrimidin-2-Yl)-6-Fluoro-2-Methyl-1H-Benzo[D]Imidazole is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters because it provides a critical, structurally defined building block essential for developing next-generation therapeutics, ensuring process consistency and regulatory compliance. It is primarily needed by R&D scientists and process chemists in the pharmaceutical and biotechnology industries working on novel drug candidates, particularly in oncology and antiviral research.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step production of target drug molecules.
• Oncology Drug Development: Used in the research and synthesis of potential chemotherapeutic agents and targeted cancer therapies.
• Antiviral Agent Synthesis: Serves as a core scaffold for constructing novel antiviral compounds.
• Kinase Inhibitor Research: Employed in the discovery and development of protein kinase inhibitors due to the benzimidazole-pyrimidine core structure.
• Chemical Biology & Proteomics: Utilized as a tool compound or a tagged ligand for studying enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the cGMP production of clinical trial materials and commercial APIs.

Basic Information

Item	Detail
Product Name	1-(4,6-Dichloro-5-Fluoropyrimidin-2-Yl)-6-Fluoro-2-Methyl-1H-Benzo[D]Imidazole
CAS No.	1610966-63-6
Molecular Formula	C12H6Cl2F2N4
Molecular Weight	315.11 g/mol
Synonyms	1-(4,6-Dichloro-5-fluoropyrimidin-2-yl)-6-fluoro-2-methyl-1H-benzimidazole; 6-Fluoro-2-methyl-1-(4,6-dichloro-5-fluoropyrimidin-2-yl)-1H-benzimidazole; 1H-Benzimidazole, 1-(4,6-dichloro-5-fluoropyrimidin-2-yl)-6-fluoro-2-methyl-; CAS 1610966-63-6; 2-Methyl-6-fluoro-1-(4,6-dichloro-5-fluoropyrimidin-2-yl)benzimidazole
EINECS	Contact for details

Quality Control

Our 1-(4,6-Dichloro-5-Fluoropyrimidin-2-Yl)-6-Fluoro-2-Methyl-1H-Benzo[D]Imidazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) documenting full specifications are available upon request, supporting your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be stored away from light. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.