Description

cis-2-Fluorocyclopentan-1-Amine is a fluorinated chiral amine building block of significant interest in advanced organic synthesis. This compound matters for its role in introducing fluorine atoms and amine functionality into molecular scaffolds, which can dramatically alter the physicochemical and biological properties of target molecules. Pharmaceutical and agrochemical researchers need it for the development of novel active ingredients, particularly where metabolic stability and bioavailability are key design parameters.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of fluorinated drug candidates, including protease inhibitors and CNS-active compounds.
• Agrochemical Synthesis: Used in creating novel fluorinated pesticides and herbicides, where the fluorine atom can enhance lipophilicity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced materials with tailored surface properties.
• Fluorine Chemistry Studies: A valuable substrate for investigating structure-activity relationships (SAR) and novel fluorination methodologies.
• Peptidomimetics: Incorporated into peptide analogs to enhance metabolic resistance and membrane permeability.

Basic Information

Product Name	cis-2-Fluorocyclopentan-1-Amine
CAS No.	1609546-71-5
Molecular Formula	C5H10FN
Molecular Weight	103.14 g/mol
Synonyms	cis-2-Fluorocyclopentylamine; (1R,2S)-2-Fluorocyclopentan-1-amine (if applicable); (1S,2R)-2-Fluorocyclopentan-1-amine (if applicable); 2-Fluorocyclopentanamine; 1-Amino-2-fluorocyclopentane; 2-Fluoro-1-cyclopentanamine; Fluorocyclopentylamine; 1609546-71-5
EINECS	Contact for details

Quality Control

Our cis-2-Fluorocyclopentan-1-Amine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity determination, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (specify isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.