Description

(S)-4-Amino-3-Fluoro-2-Methylbutan-2-Ol CAS NO 1609546-50-0 is a high-purity, chiral fluorinated amino alcohol building block of significant interest in advanced organic synthesis. Its unique stereochemistry and functional group arrangement make it a critical intermediate for constructing complex molecules with specific biological activity. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Building block for creating advanced, enantiomerically pure herbicides, fungicides, and pesticides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands and organocatalysts for asymmetric synthesis, enhancing stereoselectivity in critical bond-forming reactions.
• Peptidomimetics and Bioactive Molecules: Incorporated into the backbone of peptide analogs and other bioactive compounds to modulate stability, bioavailability, and receptor binding.
• Fluorine Chemistry Research: Serves as a valuable substrate for studying the effects of fluorine introduction on molecular conformation and physicochemical properties in medicinal chemistry.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific custom synthesis projects.

Basic Information

Product Name	(S)-4-Amino-3-Fluoro-2-Methylbutan-2-Ol
CAS No.	1609546-50-0
Molecular Formula	C5H12FNO
Molecular Weight	121.16 g/mol
Synonyms	(2S)-4-Amino-3-fluoro-2-methylbutan-2-ol; (S)-4-Amino-3-fluoro-2-methyl-2-butanol; 2-Butanol, 4-amino-3-fluoro-2-methyl-, (2S)-; 1609546-50-0; (S)-3-Fluoro-4-amino-2-methyl-2-butanol; 4-Amino-3-fluoro-2-methyl-2-butanol (S-enantiomer); (S)-Amino Fluoro Methyl Butanol
EINECS	Contact for details

Quality Control

Our (S)-4-Amino-3-Fluoro-2-Methylbutan-2-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and enantiomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.