Description

4-Amino-3,3-difluoro-2-methylbutan-2-ol is a specialized fluorinated amino alcohol building block of significant interest in advanced organic synthesis. Its unique structure, featuring both amino and fluorine substituents, makes it a valuable precursor for constructing complex molecules with tailored properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Serves as a building block for creating advanced herbicides, fungicides, and insecticides, where the fluorine atoms can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorinated Amino Acid Analogues: Acts as a precursor in the synthesis of fluorinated amino acids and peptides for biochemical and biophysical studies.
• Material Science Research: Employed in the development of novel fluorinated polymers and specialty chemicals with unique surface properties.

Basic Information

Product Name	4-Amino-3,3-difluoro-2-methylbutan-2-ol
CAS No.	1609546-43-1
Molecular Formula	C5H11F2NO
Molecular Weight	139.14 g/mol
Synonyms	2-Methyl-4-amino-3,3-difluorobutan-2-ol; 3,3-Difluoro-2-methyl-4-aminobutan-2-ol; 4-Amino-3,3-difluoro-2-methyl-2-butanol; Amino-difluoromethylbutanol; DFMAB
EINECS	Contact for details

Quality Control

Our 4-Amino-3,3-difluoro-2-methylbutan-2-ol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) with full batch traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.