Description

Mc-Gly-Gly-Phe-Gly-Nh-Ch2-o-Ch2Cooh is a synthetic peptide derivative, specifically a modified tetrapeptide sequence, identified by CAS No. 1599440-25-1. This compound serves as a crucial building block and intermediate in advanced pharmaceutical research and development, particularly in the design of novel therapeutic agents and diagnostic tools. It is primarily utilized by research institutions, biotechnology firms, and pharmaceutical companies engaged in peptide-based drug discovery, proteomics, and biochemical assay development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex peptide-based active pharmaceutical ingredients (APIs) and prodrugs.
• Bioconjugation & Probe Development: Used for creating labeled peptides and probes for biochemical assays, imaging, and diagnostic applications due to its reactive terminal group.
• Enzyme Substrate & Inhibitor Design: Serves as a substrate analog or inhibitor scaffold in enzymatic studies and high-throughput screening for drug discovery.
• Peptide Library Synthesis: An essential component in combinatorial chemistry for generating diverse peptide libraries to study structure-activity relationships (SAR).
• Biomaterial Functionalization: Employed to modify surfaces and biomaterials to enhance biocompatibility or introduce specific biological activity.
• Academic & Industrial Research: A valuable tool for fundamental research in biochemistry, molecular biology, and medicinal chemistry.

Basic Information

Product Name	Mc-Gly-Gly-Phe-Gly-Nh-Ch2-o-Ch2Cooh
CAS No.	1599440-25-1
Molecular Formula	C21H28N6O7
Molecular Weight	476.48 g/mol
Synonyms	N-Acetyl-Glycyl-Glycyl-L-Phenylalanyl-Glycine Amide Acetic Acid; Ac-Gly-Gly-Phe-Gly-NH-CH2-O-CH2-COOH; Ac-GGFG-NH-(CH2)2-O-CH2-COOH; (2-{2-[2-(2-Acetamidoacetamido)-3-phenylpropanamido]acetamido}ethoxy)acetic Acid; Tetrapeptide Derivative GGFG; N-Ac-GGFG-NH-PEG1-CH2COOH; Peptide Spacer Molecule; Custom Peptide Intermediate
EINECS	Contact for details

Quality Control

Our Mc-Gly-Gly-Phe-Gly-Nh-Ch2-o-Ch2Cooh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and NMR for structural verification, to ensure compliance with research-grade specifications. Certificates of Analysis (COA) detailing all test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing at -20°C under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC-MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.