Description

Mc-Gly-Gly-Phe CAS NO 1599440-15-9 is a high-purity tripeptide derivative, specifically a methionine-capped glycyl-glycyl-phenylalanine sequence. This compound serves as a critical building block and intermediate in advanced pharmaceutical research and peptide synthesis. It is primarily utilized by R&D scientists and process chemists in the biotechnology and pharmaceutical industries for developing novel therapeutic agents and diagnostic tools.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Bioconjugation & Probe Development: Used in the creation of labeled peptides for biochemical assays, imaging probes, and diagnostic reagents.
• Medicinal Chemistry Research: Serves as a scaffold or precursor in structure-activity relationship (SAR) studies for drug discovery programs.
• Enzyme Substrate Analog: Potential use as a substrate or inhibitor in enzymatic studies, particularly for proteases and peptidases.
• Cosmeceutical Peptide Synthesis: Intermediate for the production of bioactive peptides used in advanced skincare and cosmetic formulations.

Basic Information

Product Name	Mc-Gly-Gly-Phe
CAS No.	1599440-15-9
Molecular Formula	C₁₇H₂₃N₃O₅S
Molecular Weight	381.45 g/mol
Synonyms	Methionyl-glycyl-glycyl-L-phenylalanine; N-Methionylglycylglycyl-L-phenylalanine; L-Phenylalanine, N-[N-[N-[(2S)-2-amino-4-(methylthio)-1-oxobutyl]glycyl]glycyl]-; Mc-GGF; MGGP; Boc-Met-Gly-Gly-Phe-OH (related protected form); Fmoc-Met-Gly-Gly-Phe-OH (related protected form); N-Met-Gly-Gly-Phe
EINECS	Contact for details

Quality Control

Our Mc-Gly-Gly-Phe is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation by mass spectrometry (MS) and infrared spectroscopy (IR). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP guidelines for early-phase development.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or refrigerated (2-8°C) for long-term stability. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Assay (Titration)	97.0% - 102.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.