Description

(2-(2-Hydroxypropan-2-Yl)Pyrimidin-5-Yl)Boronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing active pharmaceutical ingredients (APIs), novel crop protection agents, and organic electronic materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in constructing complex heterocyclic scaffolds for new-generation herbicides, fungicides, and insecticides.
• Material Science: Serves as a precursor in the development of organic light-emitting diodes (OLEDs), semiconductors, and metal-organic frameworks (MOFs).
• Chemical Synthesis: Enables the formation of carbon-carbon bonds in Suzuki-Miyaura cross-coupling reactions to create complex, functionalized molecules.
• Ligand & Catalyst Development: Utilized in the preparation of specialized ligands for catalysis and molecular recognition applications.
• Academic & R&D: A valuable reagent for methodological development and exploratory research in organic and medicinal chemistry laboratories.

Basic Information

Item	Details
Product Name	(2-(2-Hydroxypropan-2-Yl)Pyrimidin-5-Yl)Boronic Acid
CAS No.	1598437-05-8
Molecular Formula	C7H11BN2O3
Molecular Weight	181.99 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(2-hydroxypropan-2-yl)pyrimidine; 2-(2-Hydroxypropan-2-yl)pyrimidine-5-boronic acid; 2-(1-Hydroxy-1-methylethyl)-5-pyrimidineboronic acid; 2-(2-Hydroxy-2-propanyl)-5-pyrimidineboronic acid; (2-(2-Hydroxy-2-propyl)pyrimidin-5-yl)boronic acid; 5-Borono-2-(2-hydroxy-2-propyl)pyrimidine; Pinacol ester of (2-(2-Hydroxypropan-2-yl)pyrimidin-5-yl)boronic acid (common protected form)
EINECS	Contact for details

Quality Control

Our (2-(2-Hydroxypropan-2-Yl)Pyrimidin-5-Yl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance in sensitive coupling reactions. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.