Description

2-(1-Phenyl-Cyclopropylamino)-Pyrimidine-5-Carboxylic Acid Ethyl Ester is a high-value, nitrogen-containing heterocyclic building block of significant interest in advanced organic synthesis. Its core structure, featuring a pyrimidine ring linked to a phenyl-cyclopropylamino moiety, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors, where it serves as a key precursor in the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Chemical Research & Development: Serves as a versatile building block in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential use in the synthesis of organic semiconductors, ligands for catalysis, or specialty polymers.
• Contract Manufacturing (CMO): Supplied to custom synthesis organizations for scale-up and production under cGMP conditions for clinical trial materials.
• Academic Research: Utilized in university and institutional labs for methodological development and exploring new chemical reactions.

Basic Information

Product Name	2-(1-Phenyl-Cyclopropylamino)-Pyrimidine-5-Carboxylic Acid Ethyl Ester
CAS No.	1598426-03-9
Molecular Formula	C₁₆H₁₇N₃O₂
Molecular Weight	283.33 g/mol
Synonyms	Ethyl 2-[(1-phenylcyclopropyl)amino]pyrimidine-5-carboxylate; 2-[(1-Phenylcyclopropyl)amino]pyrimidine-5-carboxylic Acid Ethyl Ester; 2-(1-Phenylcyclopropylamino)pyrimidine-5-carboxylic Acid Ethyl Ester; 1598426-03-9; UNII-9W6S5A8Z4K; 9W6S5A8Z4K; AKOS040759416; SCHEMBL21806227; DB15499
EINECS	Contact for details

Quality Control

Our 2-(1-Phenyl-Cyclopropylamino)-Pyrimidine-5-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications. Custom purity grades, including research and cGMP standards, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0% (Research Grade)
Purity (HPLC)	≥98.0% (Premium Grade)
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.