Description

2-Aminopyrimidine-5-Carbaldehyde Hydrate is a high-purity, functionalized pyrimidine building block essential for advanced organic synthesis. This compound matters for its role as a key precursor in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its aldehyde and amine functionalities enable diverse chemical transformations. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of kinase inhibitors, antiviral agents, and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Research: Serves as a versatile starting material in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal catalysis and organocatalysts.
• Material Science Precursor: Potential use in the synthesis of organic semiconductors and functional polymers.

Basic Information

Product Name	2-Aminopyrimidine-5-Carbaldehyde Hydrate
CAS No.	1588441-19-3
Molecular Formula	C5H7N3O2
Molecular Weight	141.13 g/mol (Anhydrous basis)
Synonyms	5-Formyl-2-pyrimidinamine hydrate; 2-Amino-5-formylpyrimidine hydrate; 5-Pyrimidinecarboxaldehyde, 2-amino-, hydrate; 2-Amino-5-pyrimidinecarboxaldehyde hydrate; 2-Aminopyrimidine-5-carboxaldehyde hydrate; 5-Aldehydo-2-aminopyrimidine hydrate
EINECS	Contact for details

Quality Control

Our 2-Aminopyrimidine-5-Carbaldehyde Hydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting cGMP and ISO standards for traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture and oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.