Description

4-(Trifluoromethoxy)-2-(Trifluoromethyl)Aniline Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoromethyl and trifluoromethoxy substituents. This compound matters as a critical building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring enhanced metabolic stability and bioavailability. It is primarily needed by research and development teams and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries for creating next-generation fluorinated compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, especially in oncology, CNS disorders, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where fluorine incorporation improves efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in catalytic processes and material science.
• Fluorinated Liquid Crystal Materials: A building block for high-performance electronic display components.
• Organic Synthesis Research: Employed in academic and industrial R&D for exploring new fluorination methodologies and reaction pathways.
• Dye and Pigment Intermediate: Used in the synthesis of specialized, high-stability colorants.

Basic Information

Product Name	4-(Trifluoromethoxy)-2-(Trifluoromethyl)Aniline Hydrochloride
CAS No.	1588441-12-6
Molecular Formula	C9H6ClF6NO
Molecular Weight	293.60 g/mol
Synonyms	2-(Trifluoromethyl)-4-(trifluoromethoxy)aniline hydrochloride; 4-(Trifluoromethoxy)-2-(trifluoromethyl)benzenamine hydrochloride; 2-Trifluoromethyl-4-trifluoromethoxyaniline HCl; 1-Amino-4-(trifluoromethoxy)-2-(trifluoromethyl)benzene hydrochloride; 4-Amino-3-(trifluoromethyl)phenyl trifluoromethyl ether hydrochloride; 1588441-12-6; 4-(Trifluoromethoxy)-2-(trifluoromethyl)phenylamine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethoxy)-2-(Trifluoromethyl)Aniline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.