Description

2-Bromo-3,4-Difluorobenzaldehyde is a versatile halogenated aromatic aldehyde building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both bromine and fluorine substituents adjacent to a reactive formyl group, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the difluorobenzene moiety can enhance metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as semiconductors and liquid crystals, where halogenated aromatic units are essential.
• Custom Synthesis and Contract Manufacturing: A valuable building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global R&D projects.

Basic Information

Item	Details
Product Name	2-Bromo-3,4-Difluorobenzaldehyde
CAS No.	1578156-21-4
Molecular Formula	C7H3BrF2O
Molecular Weight	221.00 g/mol
Synonyms	3,4-Difluoro-2-bromobenzaldehyde; 2-Bromo-3,4-difluorobenzenecarboxaldehyde; Benzaldehyde, 2-bromo-3,4-difluoro-; 1578156-21-4; 2-Bromo-3,4-difluoro benzaldehyde
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-3,4-Difluorobenzaldehyde is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of your synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its sensitivity to light and propensity for oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.