Description

2-(6-Fluoro-2-Methyl-4-Oxoquinazolin-3(4H)-Yl)-n-(Pyridin-4-Ylmethyl)Acetamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound matters as a key building block in modern medicinal chemistry, enabling the development of targeted therapies with specific biological activity. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in drug discovery and development, particularly for oncology and antiviral applications.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel quinazoline-based drug candidates.
• Drug Discovery Research: Used in high-throughput screening and structure-activity relationship (SAR) studies for identifying new therapeutic leads.
• Kinase Inhibitor Development: Serves as a core scaffold for the development of potent and selective kinase inhibitors targeting various disease pathways.
• API Synthesis: Integrated into multi-step synthetic routes for the production of active pharmaceutical ingredients under cGMP conditions.
• Biochemical Research: Employed as a tool compound in biochemical assays to study enzyme function and cellular signaling mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	2-(6-Fluoro-2-Methyl-4-Oxoquinazolin-3(4H)-Yl)-n-(Pyridin-4-Ylmethyl)Acetamide
CAS No.	1574485-27-0
Molecular Formula	C₁₇H₁₅FN₄O₂
Molecular Weight	326.33 g/mol
Synonyms	2-[(6-Fluoro-2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)]-N-(pyridin-4-ylmethyl)acetamide; 3-[2-Oxo-2-[(pyridin-4-ylmethyl)amino]ethyl]-6-fluoro-2-methyl-3,4-dihydroquinazolin-4-one; 1574485-27-0; 6-Fluoro-2-methyl-3-[2-oxo-2-(4-pyridylmethylamino)ethyl]-4(3H)-quinazolinone; N-(4-Pyridinylmethyl)-2-(6-fluoro-2-methyl-4-oxo-3(4H)-quinazolinyl)acetamide
EINECS	Contact for details

Quality Control

Our 2-(6-Fluoro-2-Methyl-4-Oxoquinazolin-3(4H)-Yl)-n-(Pyridin-4-Ylmethyl)Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance with research and cGMP standards for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.