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2-(6-Fluoro-2-Methyl-4-Oxoquinazolin-3(4H)-Yl)-n-(2-Hydroxyethyl)Acetamide CAS NO 1574321-43-9
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CAS No.:1574321-43-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-(6-Fluoro-2-Methyl-4-Oxoquinazolin-3(4H)-Yl)-n-(2-Hydroxyethyl)Acetamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound matters for its role as a critical building block in medicinal chemistry, enabling the development of targeted therapeutics with specific biological activity. Pharmaceutical R&D teams and fine chemical manufacturers need this material for creating innovative drug candidates, particularly in oncology and other specialized therapeutic areas.
Application
- Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinazolinone-based active pharmaceutical ingredients (APIs).
- Oncology Drug Research: Used in the development of targeted cancer therapies, leveraging its specific molecular scaffold.
- Medicinal Chemistry R&D: Serves as a versatile building block for structure-activity relationship (SAR) studies and lead optimization.
- Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex, high-value molecules.
- Biochemical Research: Utilized as a tool compound in biochemical assays to study enzyme inhibition or receptor binding.
- Contract Manufacturing (CMO/CDMO): Supplied to contract development and manufacturing organizations for cGMP production of clinical trial materials.
Basic Information
| Product Name | 2-(6-Fluoro-2-Methyl-4-Oxoquinazolin-3(4H)-Yl)-n-(2-Hydroxyethyl)Acetamide |
| CAS No. | 1574321-43-9 |
| Molecular Formula | C₁₃H₁₄FN₃O₃ |
| Molecular Weight | 279.27 g/mol |
| Synonyms | 2-[(6-Fluoro-2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)]-N-(2-hydroxyethyl)acetamide; 3-[2-[(2-Hydroxyethyl)amino]-2-oxoethyl]-6-fluoro-2-methyl-3,4-dihydroquinazolin-4-one; 1574321-43-9; 6-Fluoro-2-methyl-3-[2-oxo-2-[(2-hydroxyethyl)amino]ethyl]quinazolin-4(3H)-one; N-(2-Hydroxyethyl)-2-(6-fluoro-2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)acetamide |
| EINECS | Contact for details |
Quality Control
Our 2-(6-Fluoro-2-Methyl-4-Oxoquinazolin-3(4H)-Yl)-n-(2-Hydroxyethyl)Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical development. Certificates of Analysis (COA) with full traceability are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to reference spectrum |
| Identification (HPLC) | Retention time matches reference standard |
| Purity (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 1.0% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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