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2-(6-Fluoro-2-Methyl-4-Oxoquinazolin-3(4H)-Yl)-n-(2-Hydroxyethyl)Acetamide CAS NO 1574321-43-9


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CAS No.:1574321-43-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-(6-Fluoro-2-Methyl-4-Oxoquinazolin-3(4H)-Yl)-n-(2-Hydroxyethyl)Acetamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound matters for its role as a critical building block in medicinal chemistry, enabling the development of targeted therapeutics with specific biological activity. Pharmaceutical R&D teams and fine chemical manufacturers need this material for creating innovative drug candidates, particularly in oncology and other specialized therapeutic areas.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinazolinone-based active pharmaceutical ingredients (APIs).
  • Oncology Drug Research: Used in the development of targeted cancer therapies, leveraging its specific molecular scaffold.
  • Medicinal Chemistry R&D: Serves as a versatile building block for structure-activity relationship (SAR) studies and lead optimization.
  • Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex, high-value molecules.
  • Biochemical Research: Utilized as a tool compound in biochemical assays to study enzyme inhibition or receptor binding.
  • Contract Manufacturing (CMO/CDMO): Supplied to contract development and manufacturing organizations for cGMP production of clinical trial materials.

Basic Information

Product Name 2-(6-Fluoro-2-Methyl-4-Oxoquinazolin-3(4H)-Yl)-n-(2-Hydroxyethyl)Acetamide
CAS No. 1574321-43-9
Molecular Formula C₁₃H₁₄FN₃O₃
Molecular Weight 279.27 g/mol
Synonyms 2-[(6-Fluoro-2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)]-N-(2-hydroxyethyl)acetamide; 3-[2-[(2-Hydroxyethyl)amino]-2-oxoethyl]-6-fluoro-2-methyl-3,4-dihydroquinazolin-4-one; 1574321-43-9; 6-Fluoro-2-methyl-3-[2-oxo-2-[(2-hydroxyethyl)amino]ethyl]quinazolin-4(3H)-one; N-(2-Hydroxyethyl)-2-(6-fluoro-2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)acetamide
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Quality Control

Our 2-(6-Fluoro-2-Methyl-4-Oxoquinazolin-3(4H)-Yl)-n-(2-Hydroxyethyl)Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical development. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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