Description

3,4-Difluoro-2-Propan-2-Yloxybenzaldehyde is a high-purity, fluorinated aromatic aldehyde building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both aldehyde and isopropoxy ether functionalities on a difluorinated benzene ring, makes it a versatile and valuable intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, where the introduction of fluorine atoms is a key strategy to modulate biological activity, metabolic stability, and lipophilicity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, anti-inflammatory agents, and CNS-active compounds.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the difluoro and alkoxy substituents contribute to enhanced bioactivity and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in advanced electronic displays and organic light-emitting diodes (OLEDs).
• Functional Material Chemistry: Employed in the development of specialty polymers, ligands for catalysis, and advanced organic frameworks where specific electronic and steric properties are required.
• Custom Synthesis & Contract Manufacturing: An essential reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	3,4-Difluoro-2-Propan-2-Yloxybenzaldehyde
CAS No.	1557552-44-9
Molecular Formula	C10H10F2O2
Molecular Weight	200.18 g/mol
Synonyms	2-Isopropoxy-3,4-difluorobenzaldehyde; 3,4-Difluoro-2-isopropoxybenzaldehyde; Benzaldehyde, 3,4-difluoro-2-(1-methylethoxy)-; 2-(Propan-2-yloxy)-3,4-difluorobenzaldehyde
EINECS	Contact for details

Quality Control

Our 3,4-Difluoro-2-Propan-2-Yloxybenzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (GC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.