Description

4-Chloro-3-Fluoro-2-Methoxybenzaldehyde is a high-purity, multi-functional aromatic aldehyde building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers requiring a reliable, high-quality precursor for constructing heterocyclic compounds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging the fluorine and chlorine substituents for enhanced bioactivity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for synthesizing specialized aromatic cores used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Complex Ligand & Catalyst Development: Employed in the creation of sophisticated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Dyestuff & Pigment Intermediate: Utilized in the manufacture of high-performance, light-fast dyes and specialty pigments.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and process research & development (R&D) in academic and industrial laboratories.

Basic Information

Product Name	4-Chloro-3-Fluoro-2-Methoxybenzaldehyde
CAS No.	1554658-43-3
Molecular Formula	C8H6ClFO2
Molecular Weight	188.58 g/mol
Synonyms	2-Methoxy-4-chloro-3-fluorobenzaldehyde; 3-Fluoro-4-chloro-2-methoxybenzaldehyde; 4-Chloro-3-fluoro-o-anisaldehyde; 2-Methoxy-3-fluoro-4-chlorobenzaldehyde; Benzaldehyde, 4-chloro-3-fluoro-2-methoxy-; 1554658-43-3
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Fluoro-2-Methoxybenzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and reducing agents. The container should be kept tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.