Description

3-(1,1-Difluoroethyl)- Phenol is a fluorinated phenolic compound of significant interest in advanced organic synthesis. This specialty chemical serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of fluorine atoms is key to modulating biological activity and metabolic stability. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where fluorination enhances efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a precursor for fluorinated mesogens used in high-performance display technologies.
• Polymer Modification: Incorporation into polymer backbones to impart unique solubility, thermal stability, or surface properties.
• Organic Electronics: Potential building block for electron-transport materials or semiconductors in OLEDs and OFETs.
• Chemical Research: A versatile reagent for academic and industrial research exploring new fluorination methodologies and structure-activity relationships.

Basic Information

Product Name	3-(1,1-Difluoroethyl)- Phenol
CAS No.	1554368-89-6
Molecular Formula	C8H8F2O
Molecular Weight	158.15 g/mol
Synonyms	3-(1,1-Difluoroethyl)phenol; 1-(3-Hydroxyphenyl)-1,1-difluoroethane; m-(1,1-Difluoroethyl)phenol; Phenol, 3-(1,1-difluoroethyl)-; Difluoroethylphenol
EINECS	Contact for details

Quality Control

Our production of 3-(1,1-Difluoroethyl)- Phenol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We are committed to meeting the exacting standards required for pharmaceutical and agrochemical applications, with capabilities for custom purity grades upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.