Description

3-(1,2,2,2-Tetrafluoroethyl)Aniline is a specialized fluorinated aromatic amine building block of significant interest in advanced chemical synthesis. Its core value lies in the unique reactivity of the aniline group combined with the electron-withdrawing and lipophilicity-enhancing properties of the tetrafluoroethyl moiety. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by material scientists exploring advanced polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the fluorine atoms enhance biological activity and environmental stability.
• Advanced Material Precursor: Serves as a monomer or functionalization agent for high-performance polymers, liquid crystals, and specialty coatings requiring thermal and chemical resistance.
• Organic Electronics: Employed in the research and development of organic semiconductors and charge-transport materials due to its electron-deficient aromatic system.
• Fluorinated Dye & Pigment Intermediate: Acts as a building block for creating dyes and pigments with improved lightfastness and unique color properties.
• Cross-coupling Reactions: Utilized in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) to introduce fluorinated aniline motifs into complex molecular architectures.

Basic Information

Item	Details
Product Name	3-(1,2,2,2-Tetrafluoroethyl)Aniline
CAS No.	1554367-11-1
Molecular Formula	C8H7F4N
Molecular Weight	193.14 g/mol
Synonyms	3-(1,2,2,2-Tetrafluoroethyl)benzenamine; 3-(Perfluoroethyl)aniline; m-(1,2,2,2-Tetrafluoroethyl)aniline; 1-Amino-3-(1,2,2,2-tetrafluoroethyl)benzene; 3-Aminobenzotrifluoroethane; Benzenamine, 3-(1,2,2,2-tetrafluoroethyl)-; 3-(Tetrafluoroethyl)phenylamine
EINECS	Contact for details

Quality Control

Our 3-(1,2,2,2-Tetrafluoroethyl)Aniline is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.