Description

4-(1,1-Difluoroethyl)-Phenol is a fluorinated phenolic compound characterized by its unique difluoroethyl substituent. This structural feature makes it a valuable specialty intermediate for the synthesis of more complex molecules, particularly in advanced research and development. It is primarily sought by pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring fluorinated aromatic systems to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the difluoroethyl group can enhance biological activity.
• Liquid Crystal Materials: Serves as a precursor in the development of fluorinated compounds for electronic display applications.
• Polymer Modification: Acts as a monomer or additive to introduce fluorine into polymer chains, altering material properties like chemical resistance and surface energy.
• Organic Synthesis & Research: A versatile reagent in academic and industrial R&D labs for constructing complex organic molecules in medicinal and materials chemistry.

Basic Information

Product Name	4-(1,1-Difluoroethyl)-Phenol
CAS No.	1552636-45-9
Molecular Formula	C8H8F2O
Molecular Weight	158.15 g/mol
Synonyms	4-(1,1-Difluoroethyl)phenol; 1-(4-Hydroxyphenyl)-1,1-difluoroethane; p-(1,1-Difluoroethyl)phenol; Phenol, 4-(1,1-difluoroethyl)-; 1552636-45-9
EINECS	Contact for details

Quality Control

Our production of 4-(1,1-Difluoroethyl)-Phenol adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques like HPLC, GC, and NMR to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality system is designed to support cGMP requirements for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. The compound is compatible with common organic solvents but should be handled in a controlled environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.