Description

4-Cyclopropyl-6-(Piperazin-1-Yl)Pyrimidine is a high-purity, functionalized pyrimidine derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a versatile chemical building block for research and development. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries to construct novel molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Medicinal Chemistry Research: Used as a core scaffold or a functionalized fragment in drug discovery programs for structure-activity relationship (SAR) studies.
• Agrochemical Development: Serves as a building block for creating novel compounds with potential herbicidal, fungicidal, or insecticidal properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes to study biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: A starting material for the custom synthesis of complex, high-value specialty chemicals under cGMP or research-grade conditions.

Basic Information

Item	Detail
Product Name	4-Cyclopropyl-6-(Piperazin-1-Yl)Pyrimidine
CAS No.	1545121-65-0
Molecular Formula	C11H16N4
Molecular Weight	204.27 g/mol
Synonyms	6-(Piperazin-1-yl)-4-cyclopropylpyrimidine; 4-Cyclopropyl-6-piperazin-1-ylpyrimidine; 4-Cyclopropyl-6-(1-piperazinyl)pyrimidine; 4-Cyclopropyl-6-piperazin-1-yl-pyrimidine; 4-Cyclopropyl-6-(piperazin-1-yl)pyrimidine; 1545121-65-0; 6-(Piperazin-1-yl)-4-cyclopropyl-pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Cyclopropyl-6-(Piperazin-1-Yl)Pyrimidine is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.