Description

n-Benzyl-2-Chloro-7,8-Dihydro-5H-Pyrano[4,3-D]Pyrimidin-4-Amine is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrimidine class of heterocyclic compounds. This compound matters as a critical building block in medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and antiviral research programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for the discovery of new active pharmaceutical ingredients (APIs).
• Oncology Drug Development: Employed as a scaffold for creating potential kinase inhibitors and other targeted cancer therapies.
• Antiviral Agent Synthesis: Utilized in research programs aimed at developing new compounds with antiviral properties.
• Chemical Biology Probes: Acts as a core structure for developing tool compounds to study specific biological processes and protein functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production of client-specific molecules.

Basic Information

Product Name	n-Benzyl-2-Chloro-7,8-Dihydro-5H-Pyrano[4,3-D]Pyrimidin-4-Amine
CAS No.	1542711-55-6
Molecular Formula	C₁₈H₁₈ClN₃O
Molecular Weight	327.81 g/mol
Synonyms	2-Chloro-N-benzyl-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-4-amine; 4-Amino-2-chloro-N-benzyl-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine; Benzyl-(2-chloro-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-4-yl)-amine; 1542711-55-6; 2-Chloro-N-benzyl-5H,7H,8H-pyrano[4,3-d]pyrimidin-4-amine
EINECS	Contact for details

Quality Control

Our n-Benzyl-2-Chloro-7,8-Dihydro-5H-Pyrano[4,3-D]Pyrimidin-4-Amine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by HPLC, NMR, and mass spectrometry. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.