Description

2-Methylsulfanyl-5,6,7,8-Tetrahydro-Quinazoline-6-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate belonging to the quinazoline class of heterocyclic compounds. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and other specialized drug discovery pipelines. The CAS number for this product is 1542029-69-5.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Used in academic and industrial laboratories for the construction of novel quinazoline derivatives with potential biological activity.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for the production of clinical trial materials and commercial APIs.
• Biochemical Research: Potential use as a tool compound or ligand in biochemical assays to study specific enzyme interactions.

Basic Information

Product Name	2-Methylsulfanyl-5,6,7,8-Tetrahydro-Quinazoline-6-Carboxylic Acid
CAS No.	1542029-69-5
Molecular Formula	C10H12N2O2S
Molecular Weight	224.28 g/mol
Synonyms	5,6,7,8-Tetrahydro-2-(methylthio)quinazoline-6-carboxylic acid; 2-(Methylthio)-5,6,7,8-tetrahydroquinazoline-6-carboxylic acid; 6-Quinazolinecarboxylic acid, 5,6,7,8-tetrahydro-2-(methylthio)-; 1542029-69-5; 2-Methylmercapto-5,6,7,8-tetrahydroquinazoline-6-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Methylsulfanyl-5,6,7,8-Tetrahydro-Quinazoline-6-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.