Description

2,6-Difluoro-3-Formylbenzonitrile is a high-purity, multi-functional aromatic building block characterized by its reactive formyl and nitrile groups flanked by fluorine atoms. This compound matters as a critical intermediate for synthesizing complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique substitution pattern enables precise structural modifications. It is primarily needed by research chemists and process development scientists working on advanced active ingredients, novel materials, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging the fluorine atoms for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Custom Synthesis and Contract Manufacturing: An essential building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global fine chemical market.

Basic Information

Product Name	2,6-Difluoro-3-Formylbenzonitrile
CAS No.	1541976-46-8
Molecular Formula	C8H3F2NO
Molecular Weight	167.11 g/mol
Synonyms	3-Cyano-2,6-difluorobenzaldehyde; 2,6-Difluorobenzaldehyde-3-carbonitrile; 2,6-Difluoro-3-formylbenzonitrile; 1541976-46-8; 3-Formyl-2,6-difluorobenzonitrile; Benzaldehyde, 3-cyano-2,6-difluoro-; 2,6-Difluoro-3-cyanobenzaldehyde
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-3-Formylbenzonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, NMR, and MS, for comprehensive characterization and impurity profiling. Certificates of Analysis (COA) detailing purity, identity, and specific tests are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.