Description

1-[2-(Trifluoromethyl)Phenyl]Cyclobutanemethanamine is a specialized organic compound featuring a cyclobutane ring and a trifluoromethylphenyl group, serving as a key chiral amine building block in advanced synthesis. Its molecular architecture is highly valued for introducing specific steric and electronic properties into target molecules, enabling the development of novel materials and active ingredients. This high-purity intermediate is essential for research and production in the pharmaceutical and agrochemical sectors, where precise molecular control is critical.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to achieve high enantioselectivity.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with tailored properties.
• Chemical Biology & Proteomics: Acts as a versatile scaffold for designing molecular probes and inhibitors to study biological pathways.

Basic Information

Product Name	1-[2-(Trifluoromethyl)Phenyl]Cyclobutanemethanamine
CAS No.	1539951-78-4
Molecular Formula	C12H14F3N
Molecular Weight	229.24 g/mol
Synonyms	1-[(2-Trifluoromethyl)phenyl]cyclobutanemethanamine; 1-[2-(Trifluoromethyl)phenyl]cyclobutanemethylamine; Cyclobutanemethanamine, 1-[2-(trifluoromethyl)phenyl]-; α-Cyclobutyl-2-(trifluoromethyl)benzylamine; 2-(Trifluoromethyl)benzylcyclobutylamine; (1-(2-(Trifluoromethyl)phenyl)cyclobutyl)methanamine
EINECS	Contact for details

Quality Control

Our 1-[2-(Trifluoromethyl)Phenyl]Cyclobutanemethanamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure it meets the exacting standards required for pharmaceutical and advanced chemical synthesis. A detailed Certificate of Analysis (COA) providing full specifications and test results is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.