Description

3-Bromo-4-Chloro-2-Fluoroaniline is a halogenated aniline derivative, a key fluorinated aromatic building block prized for its unique substitution pattern. This compound is essential for introducing specific steric and electronic properties into target molecules during advanced synthesis. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for advanced polymers, liquid crystals, and organic electronic materials due to its halogenated aromatic structure.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) to create complex biaryl amines and other fine chemicals.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing specialized halogenated dyes and pigments with unique color fastness and properties.

Basic Information

Product Name	3-Bromo-4-Chloro-2-Fluoroaniline
CAS No.	1539469-93-6
Molecular Formula	C6H4BrClFN
Molecular Weight	224.46 g/mol
Synonyms	2-Fluoro-3-bromo-4-chloroaniline; 3-Bromo-4-chloro-2-fluoro-benzenamine; Benzenamine, 3-bromo-4-chloro-2-fluoro-; 4-Chloro-3-bromo-2-fluoroaniline; 2-Fluoro-4-chloro-3-bromoaniline; 3-Br-4-Cl-2-F-aniline
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Chloro-2-Fluoroaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and transfer should be minimized under direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.