Description

5-Cyano-2,3,4-Trifluorobenzaldehyde is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring a reactive aldehyde group adjacent to cyano and fluorine substituents, makes it a versatile precursor for constructing complex heterocycles and functional materials. This compound is primarily sought by R&D and production chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, particularly in kinase inhibitor and CNS-active molecule research.
• Agrochemical Active Ingredient Development: Used to create novel herbicides and fungicides with enhanced bioavailability and environmental stability.
• Liquid Crystal & OLED Material Synthesis: Serves as a core building block for fluorinated electron-transport materials and liquid crystal compounds.
• Advanced Polymer Chemistry: Incorporated as a monomer to impart specific polarity, solubility, and thermal properties to high-performance polymers.
• Cross-Coupling Reactions: The aldehyde and halogenated aryl ring make it suitable for Suzuki, Sonogashira, and other palladium-catalyzed coupling reactions.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new reactions and creating specialized chemical libraries.

Basic Information

Product Name	5-Cyano-2,3,4-Trifluorobenzaldehyde
CAS No.	1538819-14-5
Molecular Formula	C8H2F3NO
Molecular Weight	177.10 g/mol
Synonyms	2,3,4-Trifluoro-5-formylbenzonitrile; 2,3,4-Trifluoro-5-cyanobenzaldehyde; Benzonitrile, 2,3,4-trifluoro-5-formyl-; 5-Formyl-2,3,4-trifluorobenzonitrile; 1538819-14-5; 5-Cyano-2,3,4-trifluorobenzaldehyde
EINECS	Contact for details

Quality Control

Our 5-Cyano-2,3,4-Trifluorobenzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified for high-purity grades. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.