Description

2-Cyclopropyl-5-Fluoroaniline is a high-purity fluorinated aromatic amine building block, essential for advanced organic synthesis. Its unique structure, featuring both a cyclopropyl and a fluoro substituent, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates targeting central nervous system (CNS) disorders and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the cyclopropyl and fluoro groups contribute to biological activity and environmental stability.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers, liquid crystals, and organic electronic materials requiring specific fluorinated aromatic components.
• Chemical Biology & Proteomics: Employed as a versatile linker or tagging reagent in the design of molecular probes and activity-based protein profiling (ABPP) agents.
• Cross-Coupling Reactions: Acts as a valuable substrate in palladium-catalyzed reactions such as Buchwald-Hartwig amination for constructing complex nitrogen-containing heterocycles.

Basic Information

Product Name	2-Cyclopropyl-5-Fluoroaniline
CAS No.	1538364-89-4
Molecular Formula	C9H10FN
Molecular Weight	151.18 g/mol
Synonyms	5-Fluoro-2-cyclopropylaniline; 2-Cyclopropyl-5-fluoro-benzenamine; Benzenamine, 2-cyclopropyl-5-fluoro-; 2-Cyclopropyl-5-fluoro-phenylamine; 5-Fluoro-2-cyclopropylphenylamine; 2-Amino-4-fluoro-1-cyclopropylbenzene; 1-Cyclopropyl-4-fluoro-2-aminobenzene
EINECS	Contact for details

Quality Control

Our 2-Cyclopropyl-5-Fluoroaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment to guarantee batch-to-batch consistency and traceability for your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.