Description

(2-(4-(Methoxycarbonyl)Piperidin-1-Yl)Pyrimidin-5-Yl)Boronic Acid is a high-purity boronic acid derivative and a key synthetic intermediate in modern organic chemistry. This compound matters for its crucial role as a versatile building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. Pharmaceutical R&D and agrochemical manufacturers need it for the development of novel active ingredients, particularly in creating piperidine- and pyrimidine-containing compounds.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological disorders and metabolic diseases.
• Suzuki-Miyaura Cross-Coupling Reagent: Used as a key boronic acid partner in palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds, essential for constructing complex heterocyclic systems.
• Agrochemical Synthesis: Employed in the research and development of novel herbicides and fungicides that incorporate pyrimidine motifs for enhanced biological activity.
• Material Science Research: Serves as a precursor in the development of organic electronic materials and metal-organic frameworks (MOFs) due to its functional boronic acid group.
• Chemical Biology & Proteomics: Utilized in the design and synthesis of molecular probes and inhibitors for studying enzyme function and protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis services catering to the needs of biotechnology and specialty chemical companies.

Basic Information

Product Name	(2-(4-(Methoxycarbonyl)Piperidin-1-Yl)Pyrimidin-5-Yl)Boronic Acid
CAS No.	1536398-19-2
Molecular Formula	C12H16BN3O4
Molecular Weight	277.09 g/mol
Synonyms	5-Pyrimidineboronic acid, 2-[4-(methoxycarbonyl)-1-piperidinyl]-; 2-(4-(Methoxycarbonyl)piperidin-1-yl)pyrimidine-5-boronic acid; 1-(5-Borono-2-pyrimidinyl)-4-piperidinecarboxylic acid methyl ester; Methyl 1-(5-boronopyrimidin-2-yl)piperidine-4-carboxylate; 1536398-19-2; Boronic acid, B-[2-[4-(methoxycarbonyl)-1-piperidinyl]-5-pyrimidinyl]-; CAS 1536398-19-2
EINECS	Contact for details

Quality Control

Our (2-(4-(Methoxycarbonyl)Piperidin-1-Yl)Pyrimidin-5-Yl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every lot upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider inert atmosphere conditions to preserve optimal quality.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.