Description

5-(1-Methyl-1H-Pyrazol-4-Yl)-4-(4-Morpholinyl)-7H-Pyrrolo[2,3-D]Pyrimidine is a high-purity, advanced pharmaceutical intermediate and research chemical with the CAS number 1527473-30-8. This heterocyclic compound is valued for its complex molecular architecture, which makes it a critical building block in modern drug discovery and development. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents, particularly kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs), especially for oncology and anti-inflammatory targets.
• Kinase Inhibitor Research: Serves as a core scaffold for designing and synthesizing novel kinase inhibitors due to its privileged pyrrolopyrimidine structure.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization programs to enhance drug potency and selectivity.
• Biochemical Research: Employed as a tool compound or reference standard in biochemical assays and pharmacological studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
• Academic Research: Utilized in university and institutional laboratories for cutting-edge research in organic synthesis and drug discovery methodologies.

Basic Information

Item	Detail
Product Name	5-(1-Methyl-1H-Pyrazol-4-Yl)-4-(4-Morpholinyl)-7H-Pyrrolo[2,3-D]Pyrimidine
CAS No.	1527473-30-8
Molecular Formula	C14H16N6O
Molecular Weight	284.32 g/mol
Synonyms	4-Morpholino-5-(1-methyl-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidine; 5-(1-Methyl-1H-pyrazol-4-yl)-4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidine; 1527473-30-8; Pyrrolo[2,3-d]pyrimidine, 5-(1-methyl-1H-pyrazol-4-yl)-4-(4-morpholinyl)-7H-; 4-(4-Morpholinyl)-5-(1-methyl-1H-pyrazol-4-yl)-7H-pyrrolo[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 5-(1-Methyl-1H-Pyrazol-4-Yl)-4-(4-Morpholinyl)-7H-Pyrrolo[2,3-D]Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and pre-clinical development phases.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere in a freezer (-20°C).

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.