Description

Benzenemethanol, 4-Amino-3-Fluoro-α,α-Dimethyl- is a high-purity, fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its unique structural features, combining a benzylic alcohol, a protected amino group, and a fluorine atom, which are critical for modulating the physicochemical and biological properties of target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for introducing fluorinated motifs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the design and production of advanced pesticides and herbicides, where the fluorine atom can improve activity and environmental persistence.
• Ligand and Catalyst Development: Employed as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Acts as a monomer or functionalizing agent in the synthesis of specialty polymers and advanced organic materials.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological systems and diagnostic applications.

Basic Information

Item	Detail
Product Name	Benzenemethanol, 4-Amino-3-Fluoro-α,α-Dimethyl-
CAS No.	1524245-55-3
Molecular Formula	C9H12FNO
Molecular Weight	169.20 g/mol
Synonyms	4-Amino-3-fluoro-α,α-dimethylbenzyl alcohol; 1-(4-Amino-3-fluorophenyl)-2-methylpropan-2-ol; 2-Methyl-1-(4-amino-3-fluorophenyl)propan-2-ol; 4-Amino-3-fluoro-α,α-dimethylbenzenemethanol; (4-Amino-3-fluorophenyl)dimethylcarbinol; 3-Fluoro-4-aminobenzhydrol, dimethyl-; Fluorinated amino benzyl alcohol derivative
EINECS	Contact for details

Quality Control

Our Benzenemethanol, 4-Amino-3-Fluoro-α,α-Dimethyl- is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to handle under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.