Description

4-Ethoxy-3,5-Difluorobenzenesulfonylchloride is a high-purity, specialized organic intermediate of significant importance in modern synthetic chemistry. Its core value lies in its role as a versatile sulfonylating agent, enabling the introduction of the sulfonyl chloride functional group into target molecules. This compound is primarily needed by R&D and production chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides that incorporate sulfonylurea or sulfonamide moieties.
• Material Science Research: Employed in the creation of specialized polymers and advanced materials with tailored surface properties.
• Chemical Derivatization: Acts as a reagent for modifying other organic compounds to introduce sulfonyl groups for further functionalization or analysis.
• Laboratory Scale Synthesis: Serves as a critical reagent for medicinal chemistry and process chemistry research in academic and industrial settings.

Basic Information

Product Name	4-Ethoxy-3,5-Difluorobenzenesulfonylchloride
CAS No.	1519155-45-3
Molecular Formula	C8H7ClF2O3S
Molecular Weight	256.66 g/mol
Synonyms	3,5-Difluoro-4-ethoxybenzenesulfonyl chloride; 4-Ethoxy-3,5-difluorobenzene-1-sulfonyl chloride; 1-(Chlorosulfonyl)-2,6-difluoro-4-ethoxybenzene; Benzenesulfonyl chloride, 4-ethoxy-3,5-difluoro-; 2,6-Difluoro-4-ethoxybenzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Ethoxy-3,5-Difluorobenzenesulfonylchloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP standards where applicable to support our clients in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.