Description

2-Cyclobutylpyrazolo[1,5-A]Pyrimidine-6-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of targeted therapies for oncology and inflammatory diseases.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies for new drug discovery.
• API Development: Serves as a core scaffold in the development and scale-up of novel Active Pharmaceutical Ingredients (APIs).
• Biochemical Research: Employed as a tool compound in biochemical assays to study specific enzyme pathways and mechanisms of action.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	2-Cyclobutylpyrazolo[1,5-A]Pyrimidine-6-Carboxylic Acid
CAS No.	1517974-95-6
Molecular Formula	C₁₁H₁₁N₃O₂
Molecular Weight	217.23 g/mol
Synonyms	2-Cyclobutylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid; 6-Carboxy-2-cyclobutylpyrazolo[1,5-a]pyrimidine; Pyrazolo[1,5-a]pyrimidine-6-carboxylic acid, 2-cyclobutyl-; 1517974-95-6; 2-Cyclobutyl-6-carboxypyrazolo[1,5-a]pyrimidine; 2-Cyclobutylpyrazolo[1,5-a]pyrimidine-6-carboxylate (acid form)
EINECS	Contact for details

Quality Control

Our 2-Cyclobutylpyrazolo[1,5-A]Pyrimidine-6-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.