Description

5-Bromo-3-Chloro-2-Fluoroaniline is a high-purity, multi-halogenated aniline derivative serving as a critical building block in advanced organic synthesis. Its unique halogen substitution pattern makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the halogen atoms contribute to bioactivity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Intermediate for producing complex, light-fast azo dyes and high-performance pigments.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination, Suzuki coupling) for creating complex biaryl structures.
• Contract Research & Development (CRO/CMO): Supplied to research organizations for custom synthesis and process development projects.

Basic Information

Product Name	5-Bromo-3-Chloro-2-Fluoroaniline
CAS No.	1517200-74-6
Molecular Formula	C6H4BrClFN
Molecular Weight	224.46 g/mol
Synonyms	2-Fluoro-5-bromo-3-chloroaniline; 3-Chloro-5-bromo-2-fluoroaniline; 5-Bromo-3-chloro-2-fluoro-benzenamine; Benzenamine, 5-bromo-3-chloro-2-fluoro-; 2-Fluoro-3-chloro-5-bromoaniline; 1517200-74-6; Aniline, 5-bromo-3-chloro-2-fluoro-
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-3-Chloro-2-Fluoroaniline is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We provide full traceability and Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, ensuring compliance with your research or production specifications. Our quality commitment supports applications requiring high standards, including cGMP development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.