Description

4-Chloro-5H-Pyrrolo[3,2-D]Pyrimidin-6-Ol is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile and critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and biotechnology industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies for novel drug candidates.
• Agrochemical Development: Serves as a building block for creating new active ingredients with potential herbicidal or fungicidal properties.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Product Name	4-Chloro-5H-Pyrrolo[3,2-D]Pyrimidin-6-Ol
CAS No.	1516103-67-5
Molecular Formula	C6H4ClN3O
Molecular Weight	169.57 g/mol
Synonyms	4-Chloro-6-hydroxy-5H-pyrrolo[3,2-d]pyrimidine; 6-Hydroxy-4-chloro-5H-pyrrolo[3,2-d]pyrimidine; 4-Chloro-5,7-dihydro-6H-pyrrolo[3,2-d]pyrimidin-6-one; 1516103-67-5; 4-Chloro-6-oxo-6,7-dihydro-5H-pyrrolo[3,2-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-5H-Pyrrolo[3,2-D]Pyrimidin-6-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.