Description

3-Bromo-5-Chloro-4-Fluoroaniline is a high-purity, multi-halogenated aniline derivative serving as a critical building block in advanced organic synthesis. Its unique halogen substitution pattern makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the halogen atoms contribute to bioactivity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as a diazotization component for producing complex azo dyes and pigments with specific color fastness and light stability properties.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination, Suzuki coupling) for creating complex biaryl and aniline structures.
• Chemical Research & Development: Essential for medicinal chemistry programs and process chemistry optimization in both academic and industrial R&D laboratories.

Basic Information

Product Name	3-Bromo-5-Chloro-4-Fluoroaniline
CAS No.	1514709-58-0
Molecular Formula	C6H4BrClFN
Molecular Weight	224.46 g/mol
Synonyms	4-Fluoro-3-bromo-5-chloroaniline; 3-Bromo-5-chloro-4-fluoro-benzenamine; 1-Amino-3-bromo-5-chloro-4-fluorobenzene; Benzenamine, 3-bromo-5-chloro-4-fluoro-; 3-Br-5-Cl-4-F-aniline
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Chloro-4-Fluoroaniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment to guarantee supply consistency and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. This material is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.