Description

Imidodicarbonic Acid, 2-(3-Iodo-1H-Pyrazolo[3,4-D]Pyrimidin-4-Yl)-, 1,3-Bis(1,1-Dimethylethyl) Ester is a high-purity, advanced pharmaceutical intermediate designed for precision synthesis. This compound is critical for researchers and manufacturers developing targeted therapeutic agents, particularly in oncology and antiviral fields. It serves as a key building block for medicinal chemists requiring a protected, functionalized heterocyclic scaffold to streamline complex molecular assembly.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel kinase inhibitors and other small-molecule drug candidates targeting specific cellular pathways.
• Oncology Research: Used in the development and optimization of potent anti-cancer compounds, leveraging its pyrazolopyrimidine core structure.
• Antiviral Drug Development: Serves as a specialized scaffold for creating compounds aimed at inhibiting viral replication enzymes.
• Biochemical Tool Compound: Employed in academic and industrial research to study enzyme function and signal transduction mechanisms.
• Process Chemistry & Scale-Up: Provides a reliable, high-quality starting material for optimizing synthetic routes from milligram to kilogram scale.
• Custom Synthesis & Contract Manufacturing: An essential raw material for CDMOs (Contract Development and Manufacturing Organizations) producing APIs (Active Pharmaceutical Ingredients) for clinical trials.

Basic Information

Item	Details
Product Name	Imidodicarbonic Acid, 2-(3-Iodo-1H-Pyrazolo[3,4-D]Pyrimidin-4-Yl)-, 1,3-Bis(1,1-Dimethylethyl) Ester
CAS No.	1513882-52-4
Molecular Formula	C17H22IN5O4
Molecular Weight	487.29 g/mol
Synonyms	2-(3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-1,3-bis(tert-butoxycarbonyl)imidodicarbonate; Di-tert-butyl 2-(3-iodo-1H-pyrazolo[3,4-d]pyrimidin-4-yl)imidodicarbonate; 3-Iodo-4-((Boc)2O)-1H-pyrazolo[3,4-d]pyrimidine; 1513882-52-4; tert-Butyl (3-iodo-1H-pyrazolo[3,4-d]pyrimidin-4-yl)imidodicarbonate; Boc-protected 3-iodo-1H-pyrazolopyrimidine; N,N-Bis(tert-butoxycarbonyl)-3-iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine
EINECS	Contact for details

Quality Control

Every batch of this pharmaceutical intermediate is produced under strict quality management systems. We guarantee high chemical purity and lot-to-lot consistency through rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.