Description

2-Cyanomorpholine-4-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative, primarily utilized as a key synthetic intermediate in advanced organic synthesis. Its core value lies in enabling the efficient introduction of the sulfonamide functional group, which is critical for modulating the biological activity and physicochemical properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly those developing novel active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of sulfonamide-containing drug candidates, including kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and fungicides where the sulfonamide moiety is required for efficacy.
• Chemical Biology & Proteomics: Serves as a reactive handle for labeling or modifying biomolecules in probe development and activity-based protein profiling (ABPP).
• Material Science Research: Employed in the creation of functional polymers and advanced materials with specific surface properties.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Cyanomorpholine-4-Sulfonyl Chloride
CAS No.	1509146-41-1
Molecular Formula	C5H7ClN2O3S
Molecular Weight	210.64 g/mol
Synonyms	4-(Chlorosulfonyl)-2-cyanomorpholine; 2-Cyano-4-morpholinesulfonyl chloride; Morpholine-4-sulfonyl chloride, 2-cyano-; 2-Cyanotetrahydro-2H-1,4-thiazine 1,1-dioxide derivative
EINECS	Contact for details

Quality Control

Our 2-Cyanomorpholine-4-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (by HPLC/NMR), identity confirmation, and impurity profiles. Our quality management system is designed to meet the stringent requirements of our global B2B clientele in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.