Description

2-Bromo-5-(Difluoromethoxy)Benzaldehyde is a versatile and high-value aromatic aldehyde building block, distinguished by its bromine and difluoromethoxy substituents. This compound is critical for research and development chemists seeking to introduce specific halogenated and fluorinated motifs into complex molecular architectures. It is primarily utilized in the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its unique structure enables the fine-tuning of biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in developing novel herbicides, fungicides, and insecticides, where the difluoromethoxy group can enhance lipophilicity and bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as fluorinated polymers and liquid crystals, for advanced display technologies.
• Custom Synthesis & Contract Manufacturing: An essential building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	2-Bromo-5-(Difluoromethoxy)Benzaldehyde
CAS No.	1504952-98-0
Molecular Formula	C8H5BrF2O2
Molecular Weight	251.03 g/mol
Synonyms	5-(Difluoromethoxy)-2-bromobenzaldehyde; 2-Bromo-5-(difluoromethoxy)benzaldehyde; Benzaldehyde, 2-bromo-5-(difluoromethoxy)-; 1504952-98-0; 2-Bromo-5-difluoromethoxybenzaldehyde
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(Difluoromethoxy)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.